Friday, March 19, 2010

Vaccines against measles

   No specific treatment exist for measles and because of the extreme infectiousness of the disease, measures to control outbreaks in highly susceptible communities almost invariably fail. Preventative vaccination is the only rational approach to measles control.
   The live, attenuated measles vaccines that are now internationally available have an acceptable safety profile are effective and relatively inexpensive and may be used interchangeably in immunization programmes. Where measles vaccine has been combined with rubella vaccine (MR) or mumps and rubella vaccine (MMR) the protective immune response to the individual components remains unchanged. The use of such combined vaccines is logically and pro-grammatically sound and is recommended is areas where the disease burden of mumps and rubella is high when the vaccine coverage rates can be sustained.
   Immunization against measles is recommended for all susceptible children and adults for whom measles vaccination is not contraindicated. The vaccine should be used to prevent outbreaks rather than to try and control outbreaks. Large-scale vaccination to control ongoing outbreaks is of limited value.

Measles is an extremely contagious disease

 Merck Mmrii Vaccine 0.5Ml Measles Mumps And Rubella - Box of 10 - Model 00000468100
Measles virus is an enveloped, ribonucleic acid virus of the genus Morbillivirus, a member of the Paramyxoviridae family. It is single-stranded, of negative polarity, and is antigenically stable, and only one serotype exists. The envelope of measles virus contains haemagglutinin and fusion protein. The haemagglutinin is responsible for viral binding to the surface of host cells and the fusion protein for viral uptake into the cell. Antibodies to haemagglutinin correlate with protection against disease. Measles virus which is probably the most infectious agent causing human disease is an exclusive human pathogen and it has no animal reservoir.
Measles is an extremely contagious viral disease that affected almost every child in the world, before the widespread use of measles vaccines. Immunization with two doses of measles vaccine is recommended for all susceptible children and adults for whom measles vaccination is not contraindicated. The vaccine should be used to prevent outbreaks before disease occurs rather than large-scale vaccination to control ongoing outbreaks, which is of limited value.

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